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Alcohol’s
role in health intrigues many medical researchers. There are those who say one
or two drinks a day is good for your heart. Yet alcohol’s negative impact on
the liver is well known. Through the years, there have been numerous studies
attempting to understand the real impact of alcohol on our health. A recent
report finds a link between alcohol consumption and colorectal cancer… and the
news is not good.
Eunyoung
Cho, ScD, an assistant professor of medicine at Harvard Medical School and
associate epidemiologist at Brigham and Women’s Hospital in Boston, gathered
information from eight studies that followed subjects for up to 16 years in
North America and Europe. From this, she developed a database to evaluate
certain behaviors and health risk factors. Dr. Cho found that drinking two
alcoholic beverages a day was only slightly associated with an increased risk
for colorectal cancer, but people who drank more than three alcoholic beverages
a day had a 40% higher risk compared with people who did not drink alcohol at
all. This was true for both men and women in the study and for all types of
alcohol. The findings are especially significant, since death due to colorectal
cancer is second only to that due to lung cancer.
We
talked with Dr. Cho to discuss her findings. Because it is not unusual for
heavy drinkers to also have a poor diet, we inquired about the people in her
database. Dr. Cho responded that she made adjustments for dietary habits in
determining results of the study, as well as for smoking, age and any other
factors that had been identified as potentially impacting the findings.
According
to Dr. Cho, there are several theories about why alcohol is associated with
colorectal cancer, but many researchers think it is due to something called acetaldehyde, which is produced in the
colon. The liver converts the ethyl alcohol to acetaldehyde, which is then
further converted into harmless acetic acid. But too much acetaldehyde can
spill out into the bloodstream. Acetaldehyde is not harmless. In fact, it is more toxic than alcohol and is
responsible for the unpleasant effects of hangovers, say Dr. Cho – and it is a
known carcinogen.
References:
Eunyoung Cho, ScD, assistant professor of medicine, Harvard Medical School, and associate epidemiologist, Brigham and Women’s Hospital, both in Boston.
Andrew L. Rubman, ND, associate professor of clinical medicine, I.W. Lane College of Integrative Medicine, Winter Park, Fl, and medical director, Southbury Clinic for Traditional Medicines, Southbury, CT.
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